Deuteronomy 28:45
Moreover all these curses shall come upon thee, and shall pursue thee, and overtake thee, till thou be destroyed; because thou hearkenedst not unto the voice of the LORD thy God, to keep his commandments and his statutes which he commanded thee:
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EXPOSITORY (ENGLISH BIBLE)
(45) Till thou be destroyed.—Not exterminated. The root meaning of the word is connected with “smiting,” and the idea seems to be to crush. (Comp. 2Kings 13:7 : “The king of Syria had destroyed them, and had made them like the dust by threshing.”) This kind of destruction is consistent with what follows in Deuteronomy 28:46, and also at the end of Deuteronomy 28:48.

Deuteronomy 28:45. Moreover, all these curses — Here some critics have made a division of these prophecies, and have interpreted the preceding part as relating to the former captivity of the Jews, and the calamities which they suffered under the Chaldeans; and the remaining part as referring to their latter captivity, and the calamities which they suffered under the Romans. But “there is no need,” says Bishop Newton, “of any such distinction; there is no reason to think any such was intended by the author; several prophecies of the one part, as well as of the other, have been fulfilled at both periods; but they have all been more amply fulfilling during the latter period; and there cannot be a more lively picture than they exhibit of the state of the Jews at present.” Indeed, the present deplorable state of the Jewish nation so exactly answers these predictions, that it is an incontestable proof of the truth of the prophecy, and consequently of the divine authority of the Scriptures. And their destruction by the Romans, far more dreadful than the former, shows that their sin in rejecting Christ was more provoking to God than idolatry itself, and left them more under the power of Satan. For their captivity in Babylon cured them effectually of idolatry in seventy years. But under this last destruction they continue above eighteen hundred years incurably averse to their own Messiah, the Lord that bought them.

28:45-68 If God inflicts vengeance, what miseries his curse can bring upon mankind, even in this present world! Yet these are but the beginning of sorrows to those under the curse of God. What then will be the misery of that world where their worm dieth not, and their fire is not quenched! Observe what is here said of the wrath of God, which should come and remain upon the Israelites for their sins. It is amazing to think that a people so long the favourites of Heaven, should be so cast off; and yet that a people so scattered in all nations should be kept distinct, and not mixed with others. If they would not serve God with cheerfulness, they should be compelled to serve their enemies. We may justly expect from God, that if we do not fear his fearful name, we shall feel his fearful plagues; for one way or other God will be feared. The destruction threatened is described. They have, indeed, been plucked from off the land, ver. 63. Not only by the Babylonish captivity, and when Jerusalem was destroyed by the Romans; but afterwards, when they were forbidden to set foot in Jerusalem. They should have no rest; no rest of body, ver. 65, but be continually on the remove, either in hope of gain, or fear of persecution. No rest of the mind, which is much worse. They have been banished from city to city, from country to country; recalled, and banished again. These events, compared with the favour shown to Israel in ancient times, and with the prophecies about them, should not only excite astonishment, but turn unto us for a testimony, assuring us of the truth of Scripture. And when the other prophecies of their conversion to Christ shall come to pass, the whole will be a sign and a wonder to all the nations of the earth, and the forerunner of a general spread of true christianity. The fulfilling of these prophecies upon the Jewish nation, delivered more than three thousand years ago, shows that Moses spake by the Spirit of God; who not only foresees the ruin of sinners, but warns of it, that they may prevent it by a true and timely repentance, or else be left without excuse. And let us be thankful that Christ hath redeemed us from the curse of the law, by being made a curse for us, and bearing in his own person all that punishment which our sins merit, and which we must otherwise have endured for ever. To this Refuge and salvation let sinners flee; therein let believers rejoice, and serve their reconciled God with gladness of heart, for the abundance of his spiritual blessings.Contrast Deuteronomy 28:12 and Deuteronomy 28:13.37. And thou shalt become an astonishment, a proverb, and a byword, among all nations whither the Lord shall lead thee, &c.—The annals of almost every nation, for eighteen hundred years, afford abundant proofs that this has been, as it still is, the case—the very name of Jew being a universally recognized term for extreme degradation and wretchedness. No text from Poole on this verse.

Moreover, all these curses shall come upon thee,.... Before related, as well as what follow:

and shall pursue thee, and overtake thee till thou be destroyed; which though they would endeavour to flee from and escape, should not be able, since they would follow them so closely and swiftly, and overtake them, and seize upon them; see Deuteronomy 28:15,

because thou hearkenedst not unto the voice of the Lord thy God, to keep his commandments and his statutes which he commanded thee; to which disobedience all the curses are to be imputed that go before or follow after.

Moreover all these curses shall come upon thee, and shall pursue thee, and overtake thee, till thou be destroyed; because thou hearkenedst not unto the voice of the LORD thy God, to keep his commandments and his statutes which he commanded thee:
EXEGETICAL (ORIGINAL LANGUAGES)
45, 46. Return to the keynote of the section (cp. Deuteronomy 28:15), and obvious conclusion to the curses which may originally have closed here.

for a sign and for a wonder] See on Deuteronomy 4:34.

Deuteronomy 28:45The opposite of Deuteronomy 28:12 and Deuteronomy 28:13 would come to pass. - In Deuteronomy 28:46 the address returns to its commencement in Deuteronomy 28:15, with the terrible threat, "These curses shall be upon thee for a sign and for a wonder, and upon thy seed for ever," for the purpose of making a pause, if not of bringing the whole to a close. The curses were for a sign and wonder (מופת, that which excites astonishment and terror), inasmuch as their magnitude and terrible character manifested most clearly the supernatural interposition of God (vid., Deuteronomy 29:23). "For ever" applies to the generation smitten by the curse, which would remain for ever rejected, though without involving the perpetual rejection of the whole nation, or the impossibility of the conversion and restoration of a remnant, or of a holy seed (Isaiah 10:22; Isaiah 6:13; Romans 9:27; Romans 11:5).
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